The Microsoft Exchange Information Store service terminated with service-specific error %%-2147221213.

Problem:

Exchange 2010 DAG has a very high copy queue length.

Non-active node can not start Microsoft Exchange Information Store Service or System Attendant Service.

System Event log error message:

The Microsoft Exchange Information Store service terminated with service-specific error %%-2147221213.
Event ID: 7024

Solution:

1. Make sure your Windows Time Service is running (optional)
2. Note the time difference between your current local clock and domain clock.
2. Run: cmd -> "net time /set" this will pull time from your local ADC site.
3. Shutdown the VM, do not power on.
4. Check the hypervisor clock to make sure it's correct and make sure that the guest VM does not sync time with the host.
5. Wait for the time to pass noted in step 2 and power on the VM.
6. Check Microsoft Exchange Information Store and System Attendant service should be running now.